CRISPR-Cas9
A molecular tool that allows precise editing of DNA sequences in living organisms.
Also: CRISPR · genetic scissors
Definition
CRISPR-Cas9 is a revolutionary genome-editing technology that uses a guide RNA to direct the Cas9 enzyme to a specific DNA sequence, where it cuts both strands of the double helix. This allows scientists to delete, replace, or insert genetic material with unprecedented precision. Originally a bacterial immune defense system, CRISPR-Cas9 has transformed biotechnology and holds promise for treating genetic diseases.
Example
“Researchers are using CRISPR-Cas9 to edit the genes of T-cells in patients with certain blood cancers, programming the immune cells to recognize and destroy cancer cells more effectively.”
Usage Examples
- 1
“The team applied crispr-cas9 best practices to improve their biology outcomes significantly.”
- 2
“Understanding crispr-cas9 is essential for anyone building a career in STEM.”
When & How to Use
Use 'CRISPR-Cas9' when working in Biology contexts where crispr-cas9 is a revolutionary genome-editing technology that uses a guide rna to direct the cas9 enzyme to a specific dna sequence, where it cuts both strands of the double helix.
- ▸Applying crispr-cas9 principles during a biology project or initiative
- ▸Explaining crispr-cas9 to a junior team member or stakeholder unfamiliar with STEM
- ▸Evaluating options or proposals using crispr-cas9 as a decision-making criterion
Etymology & Origin
The term 'CRISPR-Cas9' derives from professional usage and entered STEM professional usage as the field formalised in the 20th century.
History & Evolution
The concept of crispr-cas9 has evolved alongside STEM. Early practitioners relied on informal methods; structured approaches emerged with the professionalisation of biology in the mid-20th century. Today, crispr-cas9 is a standard part of STEM practice globally.
Synonyms
- gene editing
- genome editing tool
- genetic scissors
Images
CC-licensed · free to useVideo
Related Terms
- Genetic Mutation
- Gene Expression
- Biotechnology
- DNA Replication